Surgery for Ischemic Stroke

Embolization of a Blood Clot

In mechanical embolectomy, a surgeon inserts a small plastic tube into an artery in the patient’s upper leg or arm and threads it under X-ray guidance into the blocked artery of the brain.

Ischemic strokes are caused by the blockage of an artery, which deprives the brain of oxygen. If an individual experiences a mild ischemic stroke, and is treated within three hours of when symptoms begin, doctors can administer the “clot-busting” medicine called t-PA to dissolve the blockage. For patients who do not arrive in the hospital in time for this treatment, or whose strokes are moderate or severe, there are surgical options for removing the clot and restoring blood flow to the brain.

Mechanical embolectomy is an advanced, minimally invasive surgical treatment designed to remove a blockage in the blood vessel. Mechanical embolectomy devices may be used routinely up to six hours after the onset of stroke symptoms (sometimes even 12 hours), although each passing hour reduces the benefits of treatment while increasing its risks.

Aspirating a intracranial blood clot

A neurosurgeon can aspirate the clot using a tiny device inserted inside the catheter.

In mechanical embolectomy,  a surgeon inserts a microcatheter (a small plastic tube) into an artery in the patient’s upper leg or wrist and threads it (under X-ray guidance) into the blocked artery of the brain. The surgeon then slips a device inside the plastic tube and advances it to the site of the clot to either aspirate it or retrieve it.

Retriever for intracranial blood clot

A retrieval device allows a neurosurgeon to remove a blood clot from the brain.

There are several devices that may be used for a mechanical embolectomy: the Penumbra device works by macerating the blockage (basically chewing it up into pieces) and then removing the pieces.  Stentrievers (such as the Solitaire and the Trevo) are designed to remove the blood clot as a whole. (The first-ever mechanical embolectomy device was called the Concentric MERCI retriever, developed 15 years ago by Dr. Y. Pierre Gobin and still in use today.)

Cerebral revascularization, also called bypass surgery, may be used if a stroke or mini-stroke was caused by “cerebrovascular insufficiency,” or a reduction in oxygen to the brain due to a blocked or narrowed carotid artery. Cerebral revascularization surgery provides new blood supply that can help prevent strokes and TIAs. Revascularization can be either direct (artery to artery) or indirect (arterial onlay to the brain surface).

Diagnosis and treatment of stroke should take place at an accredited Comprehensive Stroke Center. NewYork-Presbyterian/Weill Cornell Medical Center is such a center. Treatment options are complex and risky; therefore, treatment should be provided by experts with considerable experience in the management of stroke.

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Our Care Team

  • Chair and Neurosurgeon-in-Chief
  • Margaret and Robert J. Hariri, MD ’87, PhD ’87 Professor of Neurological Surgery
Phone: 212-746-4684
  • Associate Professor, Neurological Surgery
Phone: 718-670-1837
  • Director of Cerebrovascular Surgery and Interventional Neuroradiology
  • Associate Professor of Neurological Surgery
  • Fellowship Director, Endovascular Neurosurgery
Phone: 212-746-5149
  • Professor of Radiology in Neurological Surgery
Phone: 212-746-4998
  • Associate Professor of Radiology in Neurological Surgery (Manhattan and Queens)
  • Director of Neurointervention (NewYork-Presbyterian Queens)
Phone: 212-746-2821 (Manhattan) or 718-303-3739 (Queens)
  • Director of Cerebrovascular and Endovascular Neurosurgery, NewYork-Presbyterian Brooklyn Methodist
Phone: 718-780-3070
  • Professor of Neuropsychology in Neurological Surgery
  • Director of Neuropsychology Services
Phone: 212-746-3356
  • Clinical Neuropsychologist
  • Associate Professor of Neuropsychology in Neurological Surgery
Phone: 212-746-3356
  • Assistant Professor of Neurological Surgery (Brooklyn and Manhattan)
Phone: 212-746-2821 (Manhattan); 718-780-3070 (Brooklyn)

Reviewed by Philip E. Stieg, PhD, MD
Last reviewed/last updated: May 2024
Illustrations by Thom Graves, CMI

Weill Cornell Medicine Neurological Surgery 525 East 68 Street, Box 99 New York, NY 10065 Phone: 866-426-7787