Colloid Cyst Patient Registry and Research

At Weill Cornell Medicine we have a colloid cyst patient registry, the largest known in the world, that directly feeds into clinical questions related to these cysts. Owing to the size of this IRB-approved registry (currently more than 250 entries), research is ongoing for questions that would otherwise be impossible to answer. Features related to natural history, neurocognitive impact, familial occurrence, and predictors of progression are some of the clinical questions being studied at this time.

These recent publications from our team result from this work:

1: Lara-Reyna JJ, Uribe-Cardenas R, Perera I, Szerlip N, Giamouriadis A, Savage N; Neurosurgery. Endoscopic removal of recurrent colloid cysts 2019 Apr 12:1-6. doi: 10.3171/2018.12.JNS181859. PubMed PMID: 30978688.

2: Singh H, Burhan Janjua M, Ahmed M, Esquenazi Y, Dhandapani S, Mauer E, Schwartz TH, Souweidane MS. Factors influencing outcome in patients with colloid cysts who present with acute neurological deterioration. J Clin Neurosci. 2018 Aug;54:88-95. doi: 10.1016/j.jocn.2018.06.006. Epub 2018 Jun 12. PubMed PMID: 29907387.

3: Abdel Latif AM, Souweidane MM. Extruded contents of colloid cysts after endoscopic removal. J Neurosurg. 2016 Sep;125(3):570-5. doi: 10.3171/2015.6.JNS142676. Epub 2016 Jan 8. PubMed PMID: 26745480.

4: Margetis K, Christos PJ, Souweidane M. Endoscopic resection of incidental colloid cysts. J Neurosurg. 2014 Jun;120(6):1259-67. doi: 10.3171/2014.3.JNS131289. Epub 2014 Apr 18. PubMed PMID: 24745712.

5: Hoffman CE, Savage NJ, Souweidane MM. The significance of cyst remnants after endoscopic colloid cyst resection: a retrospective clinical case series. Neurosurgery. 2013 Aug;73(2):233-7; discussion 237-9. doi: 10.1227/01.neu.0000430300.10338.71. PubMed PMID: 23624411.

6: Margetis K, Souweidane MM. Endoscopic resection of colloid cyst in normal-sized ventricular system. Neurosurg Focus. 2013 Jan;34(1 Suppl):Video 8. doi: 10.3171/2013.V1.FOCUS12329. PubMed PMID: 23282152.

7: Margetis K, Souweidane MM. Endoscopic treatment of intraventricular cystic tumors. World Neurosurg. 2013 Feb;79(2 Suppl):S19.e1-11. doi: 10.1016/j.wneu.2012.02.021. Epub 2012 Feb 10. Review. PubMed PMID: 22381842.

8: Qiao L, Souweidane MM. Purely endoscopic removal of intraventricular brain tumors: a consensus opinion and update. Minim Invasive Neurosurg. 2011 Aug;54(4):149-54. doi: 10.1055/s-0031-1284386. Epub 2011 Sep 15. PubMed PMID:21922442.

9: Souweidane MM, Hoffman CE, Schwartz TH. Transcavum interforniceal endoscopic surgery of the third ventricle. J Neurosurg Pediatr. 2008 Oct;2(4):231-6. doi: 10.3171/PED.2008.2.10.231. PubMed PMID: 18831654.

10: Souweidane MM. Endoscopic surgery for intraventricular brain tumors in patients without hydrocephalus. Neurosurgery. 2008 Jun;62(6 Suppl 3):1042-8. doi: 10.1227/01.neu.0000333769.51069.80. PubMed PMID: 18695524.

11: Souweidane MM, Luther N. Endoscopic resection of solid intraventricular brain tumors. J Neurosurg. 2006 Aug;105(2):271-8. PubMed PMID: 17219833.

12: Souweidane MM. Endoscopic surgery for intraventricular brain tumors in patients without hydrocephalus. Neurosurgery. 2005 Oct;57(4 Suppl):312-8; discussion 312-8. PubMed PMID: 16234680.

Our Care Team

  • Vice Chair, Neurological Surgery
  • Director, Pediatric Neurological Surgery
Phone: 212-746-2363
  • Chief of Neurological Surgery, NewYork-Presbyterian Queens
  • Professor of Clinical Neurological Surgery
  • Co-director, Weill Cornell Medicine CSF Leak Program
Phone: (718) 670-1837
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  • Director of Neuropsychology Services
Phone: 212-746-3356
  • Clinical Neuropsychologist
  • Associate Professor of Neuropsychology in Neurological Surgery
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