Dr. Nadia Dahmane, PhD, has spent her career studying the relationship between developmental biology and cancer. Her work examines normal brain development, including the processes of cell differentiation and proliferation – which, when unchecked, can lead to pediatric tumor development.
Dr. Dahmane’s current research focuses a group of proteins called transcription factors that regulate how different genes are expressed during both brain development and brain cancer progression. Her laboratory has identified a critical novel transcription factor protein (called RP58) that is indispensable for brain development; its deletion in a mouse model leads to microcephaly, a birth defect affecting the size of the brain. New work from her group investigates how this protein may also be involved in brain tumor development.
Dr. Dahmane earned a B.S. in Biology and an M.S. in Biochemistry/Cell Biology from the University of Rouen, France, and she was awarded a Ph.D. in Biology of Aging by the University of Paris, France.
