Definition: 
 The largest nerve in the body. It extends from the sacral plexus, emerges from the pelvis, and travels deep within the buttocks. It then descends down the back of the thigh to the back of the knee, at which point it divides into the common peroneal and tibial nerves. The sciatic nerve supplies sensation to the back of the thigh, outer side of the leg, and essentially the whole foot.